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Interactions

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Considering drug interactions with smoking

31 October 2023Tobacco smoke can induce liver enzymes, affecting drug metabolism. Some medicines may need dose adjustment or monitoring if a person stops or starts smoking.

Drug interactions: resources to support answering questions

19 January 2023Suggested resources to help primary care healthcare professionals find information to answer questions about drug interactions

Herbal interactions: resources to support answering questions

28 March 2024Suggested resources to help healthcare professionals find information to answer questions about herbal interactions.

Identifying risk factors for developing a long QT interval

29 March 2023Some medicines (erythromycin, citalopram, ondansetron) can cause a long QT interval. Consider risk factors and follow MHRA recommendations for safe use.

Interactions

All our advice relating to medicine interactions, with recommendations on management options.

Managing interactions between macrolides and statins

24 November 2023The use of statins can be continued with azithromycin. However, the interaction risks need to be managed if clarithromycin or erythromycin are required.

Managing interactions with direct oral anticoagulants (DOACs)

5 January 2024Interactions with apixaban, dabigatran, edoxaban or rivaroxaban can result in increased risks of a bleed or thrombosis. We advise on management options.

Managing interactions with methotrexate

28 December 2023Guidance on frequently asked questions on medicine interactions with low dose methotrexate.

Managing specific interactions with smoking

31 October 2023When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

Questions to ask when reviewing herbal medicines and interactions

28 March 2024Information should be gathered about the patient and herbal medicine to enable risk assessment and decision making on the interaction.