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Excipients

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Update on development of biosimilar versions of adalimumab with particular focus on excipients and injection site reactions

18 January 2019An overview of the five versions of adalimumab currently available in the UK. These article focuses on the differences in excipients and in particular the…

Is there a lactose-free oral contraceptive?

29 March 2019All licensed oral contraceptives currently available on prescription contain lactose. This Medicines Q&A lists lactose-free, non-oral alternatives.

Excipients: What are the general considerations for vegan patients?

19 July 2019Excipients are used in the manufacture of medicines for various purposes and may be derived from animals. It may not be obvious from the Summary…

Is there a lactose-free antidepressant?

24 September 2019This Medicine Q&A lists currently available lactose-free antidepressant preparations. There is a lactose-free preparation available for all antidepressants except for clomipramine, doxepin, isocarboxazid, moclobemide, nortriptyline…

What are the excipients in toothpastes?

3 December 2019Toothpastes contain excipients that can cause adverse reactions affecting the mouth and lips, and systemic hypersensitivity. Excipients most commonly implicated are flavourings such as spearmint,…

Ethanol content of inhalers – What is the significance?

13 December 2019Ethanol is included as an excipient in many commonly prescribed inhalers, including some licensed for use in children.  Patients may have ethical, religious or cultural…

Drugs for urinary disorders – are any lactose-free?

5 February 2020This Medicine Q&A gives details of available urinary frequency, enuresis, incontinence and urinary retention preparations that do not contain lactose. There is a lactose-free preparation…

Is there a lactose-free hormone replacement therapy (HRT)?

24 February 2020This Medicines Q&A provides a summary of the currently available HRT preparations that contain lactose and suggests options for lactose-free alternatives.

What factors need to be considered when prescribing for lactose intolerant adults?

24 February 2020This Medicines Q&A discusses the types of lactose intolerance people may suffer from, how to determine the lactose content of medicines, and what factors healthcare…

Oral antihistamines – which are available in lactose-free formulations?

28 September 2020This updated Medicines Q&A includes a table which gives details of oral, single active constituent, antihistamine preparations that have lactose free formulations.