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Safety in Lactation: Drugs for thromboembolic disorders

18 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral anticoagulants The coumarin anticoagulants, warfarin…

What factors should be considered when using LMWH to treat venous thromboembolism in patients with high body weight?

14 September 2020Treatment of venous thromboembolism (VTE) in patients with high body weight constitutes a challenge in clinical practice. Adjustments in the dose calculation may be necessary…

Maintaining Patency of Central Venous Catheters in Adults: RMOC Position Statement

11 February 2019The Regional Medicines Optimisation Committee (RMOC) (London) reviewed the role of heparinised saline lock versus sodium chloride 0.9% lock for maintaining patency of central venous…

How should medicines be dosed in children who are obese?

18 October 2018Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…

Common Questions and Answers on the Practical Use of Oral Anticoagulants in Non-Valvular Atrial Fibrillation (Jan 2016)

14 September 2016Please note – the content of this resource has not been updated since the publication date. Some information may be out of date and links…

ARCHIVED NPSA Alert – Reducing treatment dose errors with low molecular weight heparins 2010

30 July 2010This page forms part of a resource on medication related patient safety alerts issued  by the National Patient Safety Agency (NPSA) between 2002 and 2012…

ARCHIVED NPSA Alert – Intravenous heparin flush solutions 2008

24 April 2008This page forms part of a resource on medication related patient safety alerts issued  by the National Patient Safety Agency (NPSA) between 2002 and 2012…