What naloxone doses should be used in adults to urgently reverse the effects of opioids?

The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range…

In use product safety assessment report: naloxone products for emergency opiate reversal in non-medical settings

A UKMi Product Safety assessment on naloxone products for emergency opiate reversal in non-medical settings; in-use medication safety considerations resultant from the product presentation or…

Safety in Lactation: Antagonists for central and respiratory depression

Flumazenil is indicated for the reversal of the sedative effects of benzodiazepines. Naloxone is indicated for the treatment opioid-induced respiratory depression. If the clinical situation…