How should medicines be dosed in children who are obese?

Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…

Shortage of Phenobarbital Sodium Injection

Martindale Pharma, the sole supplier of phenobarbital sodium injection is out of stock of 30mg in 1mL (with no dates for resupply) and 60mg in…

Can antiepileptics (anticonvulsants) increase the risk of osteoporosis?

This updated Medicines Q&A evaluates the evidence available on the risk of osteoporosis in patients with epilepsy taking antiepileptic drugs.

Safety in Lactation: Drugs used in status epilepticus

Choice of treatment will be influenced by the clinical situation. The evidence for these drugs in breastfeeding is based on their longer-term use rather than…