Shortage of capsaicin cream (Zacin and Axsain)

Teva, the sole supplier of these two products, is out of stock until at least November 2019. At present it seems possible to import supplies…

Shortage of suxamethonium chloride Injection BP 100 mg in 2 ml

Over the past few months there have been intermittent supply issues. Suppliers have been supporting one another over this period. Martindale, who have been supporting…

Shortage of Actiq lozenges and Instanyl nasal spray (immediate-release fentanyl citrate)

Actiq lozenges and Instanyl nasal spray are both licensed for the treatment of breakthrough pain in adults with cancer who are already receiving maintenance opioid…

Which opioids can be used in renal impairment?

Opioids are used in a wide variety of clinical settings and are well established for the treatment of both acute and chronic pain. Renal impairment…

New Medicines Newsletter June 2018

New Medicines Newsletter is produced by the UKMi horizon scanning service. It highlights recent significant medicines regulatory changes and new medicines monographs added to the…

In use product safety assessment report for Zalviso® (sufentanil citrate) sublingual tablets

A UKMi Product Safety assessment on Zalviso® (sufentanil citrate) sublingual tablets which describes the in-use medication safety considerations resultant from the product’s presentation or other…

Shortage of Xylocaine (lidocaine) 10 mg Spray

Aspen, the sole supplier, is out of stock again until some point in May.  This memo provides advice on how to manage the shortage and…

In use product safety assessment report: Onexila® XL (oxycodone once daily prolonged release tablets)

A UKMi Product Safety assessment on Onexila® XL (oxycodone once daily prolonged release tablets); in-use medication safety considerations resultant from the product presentation or other…