NICE Bites – Cannabis-based medicinal products

Please go to www.nice.org.uk to check for any recent updates to this guideline.   NICE Bites is a monthly prescribing bulletin published by North West…

Shortage of capsaicin cream (Zacin and Axsain)

Teva, the sole supplier of these two products, is out of stock until at least November 2019. At present it seems possible to import supplies…

Shortage of suxamethonium chloride Injection BP 100 mg in 2 ml

Over the past few months there have been intermittent supply issues. Suppliers have been supporting one another over this period. Martindale, who have been supporting…

Shortage of Actiq lozenges and Instanyl nasal spray (immediate-release fentanyl citrate)

Actiq lozenges and Instanyl nasal spray are both licensed for the treatment of breakthrough pain in adults with cancer who are already receiving maintenance opioid…

Which opioids can be used in renal impairment?

Opioids are used in a wide variety of clinical settings and are well established for the treatment of both acute and chronic pain. Renal impairment…

In use product safety assessment report for Zalviso® (sufentanil citrate) sublingual tablets

A UKMi Product Safety assessment on Zalviso® (sufentanil citrate) sublingual tablets which describes the in-use medication safety considerations resultant from the product’s presentation or other…