Administration of tobramycin via a nebuliser

If there are robust clinical reasons to administer tobramycin injection via a nebuliser instead of using the licensed nebuliser solution then it is critical that a phenol-free formulation of the injection is used. Currently there are two formulations of tobramycin injection available in the UK – one from Pfizer/ Hospira which is phenol-free and one from Flynn which contains phenol as an excipient.  This document outlines the risks associated with using the injection instead of the nebuliser solution for this indication.

NewsRespiratory disordersTobramycin