Alfentanil hydrochloride: syringe compatibility information for use during COVID-19

During COVID-19 mixing drugs in a syringe may be more necessary than normal.  For our background page on syringe compatibility during COVID-19 go here.

Alfentanil hydrochloride is a solution for injection with an acid pH.

This page gives specific information on compatibility of alfentanil hydrochloride when combined with other medicines in a syringe.  Use this information in conjunction with the detailed information on alfentanil hydrochloride in the national injectable medicines guide.

Known compatibility information for alfentanil hydrochloride

  • Compatible with the Diprivan brand of propofol 1% for up to 6 hours, at a concentration of up to 0.5mg/mL of alfentanil hydrochloride and up to 10mg/mL of propofol
  • Compatible with midazolam hydrochloride for up to 24 hours, at a concentration of up to 0.5mg/mL of alfentanil hydrochloride and up to 0.2mg/mL of midazolam, with sodium chloride 0.9% used as a diluent
  • Compatible with midazolam hydrochloride for up to 12 hours, at a concentration of up to 2.7mg/mL of alfentanil hydrochloride and up to 1.1mg/mL of midazolam, with sodium chloride 0.9% used as a diluent

The information on this page has been put together rapidly to help colleagues during the COVID-19 pandemic, if you spot anything that’s wrong or needs improving report a concern.