Using our advice

Please see Medicines suitable for adults with swallowing difficulties

The choice of medicine formulation should be made on an individual basis, taking account of patient factors. Follow our stepwise guide Choosing medicines formulations in swallowing difficulties

Licensed medicines in suitable formulations

Warfarin 1mg/1ml oral suspension

Available as a licensed preparation. It does not require fridge storage and has an expiry of 28 days once opened.

Apixaban tablets

Film-coated but are licensed to be crushed and dispersed in water, glucose 5%, apple juice or apple puree.

Dabigatran (Pradaxa) granules

Licensed to be be mixed with mashed banana, mashed carrot, apple sauce or apple juice. Do not use milk or milk-containing food products. See the product patient information leaflet for detailed administration instructions.

This preparation is only licensed for children under 18 years who are able to swallow soft food, not for adults.

Dabigatran capsules must not be opened; bioavailability of the capsule contents may be increased by 75% when taken without the shell.

Edoxaban (Lixiana) tablets

Film-coated but are licensed to be crushed and mixed with water or apple puree.

Rivaroxaban tablets

Film-coated but are licensed to be crushed and mixed with water or apple puree. Crushed 15mg and 20mg strengths should be immediately followed by food.

Rivaroxaban (Xarelto) granules for oral suspension 1mg/1ml

After reconstitution, the suspension has an expiry of 14 days. It does not require fridge storage.

This preparation is only licensed for neonates, children and young people under 18 years of age, not adults.

Licensed medicines used ‘off-label’

Warfarin tablets

Can be crushed and/or dispersed in water or crushed and given with soft food.

Apixaban, edoxaban and rivaroxaban tablets

Can be crushed and given with soft food (but are licensed to be given with apple puree/apple sauce).

Do not open dabigatran capsules. Bioavailability of dabigatran capsule contents may be increased by 75% when taken without the shell.

Special-order medicines

In view of the licensed options available, special-order preparations are unlikely to be required.

Update history