Batch Worksheets for S10 Preparation of Injectable Medicines for ICU ** Updated 05/05/2020**

These worksheets have been developed and approved by the Pharmaceutical Quality Assurance Committee (PhQAC) to support unlicensed aseptic units to safely prepare small batches of critical medicines used in ICU over the current Covid-19 emergency period.

The first set of worksheets has been prioritised for critical medicines required for ventilation. Additional worksheets will be developed for other ICU medicines including antibiotics and end of life medicines.

For further details on product shelf life, storage conditions and stability references sources used, please see the Stability reference table

For additional support on the use of these worksheets, see the guidance document COVID-19: Worksheets for batch preparation of ICU medicines in unlicensed aseptic units

A blank product template is available here to allow units to develop worksheets for products which are not listed. If a new product worksheet is developed locally it must be approved by your RQA Pharmacist.

Please direct further questions or feedback to RegionalQAQueries@rlbuht.nhs.uk

Product Final concentration Version / Format Available
Alfentanil

25mg in 50ml in Glucose 5%

500 microgram/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Atracurium

500mg in 50ml

10mg/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Cisatracurium

150mg in 30ml

5mg/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Fentanyl

500 micrograms in 10ml

50 microgram/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Insulin(Actrapid)

50 units in 50ml  in Sodium Chloride 0.9%

1unit/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Insulin (Humulin S)

50 units in 50ml  in Sodium Chloride 0.9%

1unit/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Metaraminol

25mg in 50ml in Sodium Chloride 0.9%

500 microgram/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

Midazolam

100mg in 50ml

2 mg/mL Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Morphine sulphate

100mg in 50ml in Sodium Chloride 0.9%

2mg/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

Noradrenaline

8mg in 50ml in Glucose 5%

160 microgram/ml Worksheet V1.0 PDF

Worksheet V1.0 Excel Format

Propofol

400mg in 40ml

10mg/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

Rocuronium  

100mg in 10ml

10 mg/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

Suxamethonium 

100mg in 2ml

50 mg/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

Thiopental Sodium

250mg in 20ml Water for Injection

12.5 mg/ml Worksheet V1.1 PDF

Worksheet V1.1 Excel Format

In Development – Coming Soon
Fentanyl

2.5mg in 50ml

50 microgram/ml In Development – Coming Soon
Remifentanyl

2mg in 50ml in Sodium Chloride 0.9%

50 microgram/ml In Development – Coming Soon

Attachments