Common Questions and Answers on the Practical Use of Oral Anticoagulants in Non-Valvular Atrial Fibrillation (Jan 2016)

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This summary briefing covers the following common questions

  • How do oral anticoagulants work?
  • What are their main contraindications?
  • Do the preparations contain wheat and lactose?
  • When should specific OACs be avoided?
  • What pre-testing and monitoring are necessary?
  • What doses should be given?
  • How should dose be adjusted in renal impairment?
  • Does the risk of a bleed vary between OACs?
  • Can bleeding be reversed?
  • What are the half-lives of the OACs?
  • What are the common side effects?
  • How do you switch between anticoagulants?
  • What are the main drug interactions?
  • How should the dose of OACs be adjusted when patients are having dental treatment or surgery
Acute CareApixabanDabigatran etexilateEdoxabanHeparinMedicinePrimary CareRivaroxabanWarfarin

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