Specific information for Pfizer-BioNTech and signposting to general guidance on contraindications and cautions information common to all COVID-19 vaccines
Contraindications to the vaccine
The manufacturer’s information for healthcare professionals states hypersensitivity to the active substance or to any of the excipients as a contraindication for use. Excipients are listed in section 6.1 of the manufacturer’s information.
Previously, the MHRA advised that people who had a history of anaphylaxis to vaccines, drugs or food should not receive the Pfizer COVID-19 vaccination. However, this advice changed on 31st December. Such individuals can now have the vaccine, unless they are hypersensitive to vaccine itself or any of its ingredients, as outlined in the manufacturer’s information. A summary of the reasons why the MHRA advice changed is available.
Cautions with concomitant conditions or medicines
Advice may be specific to this vaccine or common across all vaccines. Our articles covering topics in this area relevant to Pfizer-BioNTech COVID-19 Vaccine are listed and summarised below by theme.
Link to document outlining reasons for MHRA change in advice relating to contraindications to the vaccine.