Consensus guidance (involving Wave 1 and 2 CAR-T centres) on the management of acute CAR-T cell toxicities.

Purpose

This document provides guidance on the management of acute CAR-T cell toxicities to help inform the development of local guidelines and to standardise the management of acute CAR-T cell toxicities across the UK.

This is a consensus guideline developed with input from the pharmacists and consultants from the first and second wave CAR-T centres.

This guidance has been updated (September 2022) and includes input from members of the clinical subgroup of the Pan UK Pharmacy Working Group for ATMPs.

Thank you to all who have supported the development of this document.

Attachments