Moving COVID-19 Vaccine Pfizer-BioNTech Vaccines from an ULT freezer into a fridge to thaw in Trusts

Ian Allen, Pharmacy Quality Assurance Regional Specialist (NW), North West Pharmaceutical Quality AssurancePublished Last updated See all updates

A standard operating procedure is provided for moving the vaccine from an ultra-low temperature fridge to thaw and the expiry reduction process


The attached standard operating procedure describes the process of of removal of the vaccine from an ultra-low temperature freezer into a fridge to thaw, and the associated expiry date reduction process.


The attachment is presented in Word to enable adaptation locally, or as reference source to check that existing local procedures are robust and comprehensive.
Within the SOP:

  • GREEN TEXT indicates that detail is awaited, and will be added when available;
  • RED TEXT indicates where detail is to be added locally.


Other handling content for Trusts

Other COVID-19 vaccines resources

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Change history

  1. Updated to reflect availability of Comirnaty-branded product and associated changes
  1. New Pfizer thaw label image added
  1. Post thaw refrigerated expiry extended to 31 days
  1. Published