Cardiovascular medicines are the most frequently prescribed drug class in older people. Yet clinicians face challenges when prescribing or deprescribing these medicines because of the heterogenicity of function and resilience of older people. Frailty, multimorbidity, inapplicability of research evidence, frequency of adverse drug events, limited life expectancy and changing therapeutic goals add complexities to medicines optimisation.

This document provides a pragmatic framework and highlight resources to optimise medicines use when managing common cardiovascular long-term conditions (LTC) in older people living with frailty, multimorbidity and polypharmacy.

Pharmacists and other clinicians in primary and secondary care settings involved with optimising medicines in older people including structured medication reviews will find it useful.