Can low dose aspirin be used in breastfeeding mothers as an antiplatelet agent?

· UKMi
  • Limited data and pharmacokinetics indicate that low dose aspirin (defined here as 75 – 100mg daily) passes into breast milk in small amounts.

 

  • There have been no adverse events described in infants exposed to aspirin via breast milk when used as an antiplatelet agent. However, the data available for the use of aspirin whilst breastfeeding are limited and therefore it should be used with caution.  Infants exposed to aspirin via breastmilk should be monitored for side effects described in children when used in directly.

 

  • It is unknown whether the small amounts of aspirin present in breast milk following an antiplatelet dose could cause Reye’s syndrome in a breastfed infant. To minimise the risk, breastfeeding should be withheld if the infant develops a fever, or consider temporarily discontinuing the aspirin if clinically justified.

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