Preparing Casirivimab 600mg Imdevimab 600mg using 11.1mL vials

Ian Allen, Pharmacy Quality Assurance Regional Specialist (NW), North West Pharmaceutical Quality AssurancePublished Last updated See all updates

Worksheets and instructions for preparing this given dose and volume combination of Ronapreve

Ronapreve expiry changes · Update to shelf-life extensions

In January 2022, the MHRA gave permission for further shelf life extension for certain batches of both the 300mg (2.5ml) cartons and the 1332mg (11.1mL) cartons. SPS resources are currently being updated to reflect this change.


The materials attached below will support users in implementing processes for the safe preparation of Casirivimab 600mg Imdevimab 600mg using 11.1mL Vials.


Preparation in an Aseptic Unit (IV Bag)

Preparation of kits for use in clinical areas (IV Bag)

Clinical area preparation work instruction(IV Bag)

Preparation of kits for use in clinical areas (S/C Syringes)

Clinical area preparation work instruction (S/C Syringes)

Worksheets for other Ronapreve products

Change history

  1. SPSCI03h and SPSCI03f updated following change to expiry stated in January 2022 DHPC letter
  1. Supporting resources added for preparation of syringes for subcutaneous administration. Existing resources for preparation of IV bags now specifically state for intravenous infusion.
  1. Resources to support preparation of 1.2g dose using 11.1mL vials published
  1. Published