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Preparing Comirnaty 3 (THREE) concentrate

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Topics: COVID-19 vaccinePreparing

An example SOP for preparing Comirnaty 3 micrograms/dose concentrate

This article forms part of a series
  1. Managing COVID-19 Vaccines: Guidance and SOPs
    1. Ordering, receiving and storing COVID-19 vaccines
    2. Transporting COVID-19 vaccines
    3. Safe and secure handling, spillage and disposal of COVID-19 vaccines
    4. Moving COVID-19 vaccines legally within the NHS
    5. Preparing Comirnaty Original / Omicron BA.4-5
    6. Preparing Comirnaty 30 micrograms (XBB.1.5) vaccine
    7. Preparing Comirnaty 10 Concentrate vaccine
    8. Preparing Comirnaty 10 (XBB.1.5) ready to use vaccine
    9. Preparing Comirnaty 3 (THREE) concentrate
    10. Preparing VidPrevtyn Beta vaccine
    11. Preparing Spikevax Original/Omicron BA.4-5

Understanding our terminology

Comirnaty 3 micrograms/dose concentrate for dispersion for injection COVID-19 mRNA Vaccine (nucleoside modified) vaccine must be prepared carefully following the manufacturer’s instructions. We refer to it as Comirnaty 3 (THREE) concentrate in our web articles.

Each dose is 0.2mL.

Example procedure

We have produced an example template Standard Operating Procedure (SOP) for the preparation of the Comirnaty 3 (THREE) concentrate vaccine. The attachment is presented in Word to enable adaptation locally, or as reference source to check that existing local procedures are robust and comprehensive. Within the SOP, red text indicates where detail is to be added locally.

Update history

  1. Page reviewed and up to date for Autumn 2023 campaign
  1. First published
  2. Published