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Preparing Comirnaty Original / Omicron BA.4-5

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Topics: COVID-19 vaccinePreparing

An example SOP for preparing Comirnaty Original / Omicron BA.4-5 vaccine

This article forms part of a series
  1. Managing COVID-19 Vaccines: Guidance and SOPs
    1. Ordering, receiving and storing COVID-19 vaccines
    2. Transporting COVID-19 vaccines
    3. Safe and secure handling, spillage and disposal of COVID-19 vaccines
    4. Moving COVID-19 vaccines legally within the NHS
    5. Preparing Comirnaty Original / Omicron BA.4-5
    6. Preparing Comirnaty 10 Concentrate vaccine
    7. Preparing Comirnaty 3 (THREE) concentrate
    8. Preparing VidPrevtyn Beta vaccine
    9. Preparing Spikevax Original/Omicron BA.4-5

Example Procedure

Comirnaty Original / Omicron BA.4-5 vaccine must be prepared carefully following the manufacturer’s instructions.

We have produced an example template Standard Operating Procedure (SOP) for the preparation of the Comirnaty Original / Omicron BA.4-5 vaccine. The attachment is presented in Word to enable adaptation locally, or as a reference source to check that existing local procedures are robust and comprehensive. Within the SOP, red text indicates where detail is to be added locally.

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Update history

  1. Section 4.3/4.4 of SOP updated so that vaccine inversion step only takes place once and is not repeated.
  1. Section 4.4.11 Added additional explanation of why 6 hour shelf life is recommended.
  1. Published