Preparing Comirnaty Original / Omicron BA.4-5

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An example SOP for preparing Comirnaty Original / Omicron BA.4-5 vaccine

Example Procedure

Comirnaty Original / Omicron BA.4-5 vaccine must be prepared carefully following the manufacturer’s instructions.

We have produced an example template Standard Operating Procedure (SOP) for the preparation of the Comirnaty Original / Omicron BA.4-5 vaccine. The attachment is presented in Word to enable adaptation locally, or as a reference source to check that existing local procedures are robust and comprehensive. Within the SOP, red text indicates where detail is to be added locally.


Update history

  1. Page reviewed and up to date for Autumn 2023 campaign
  1. Section 4.3/4.4 of SOP updated so that vaccine inversion step only takes place once and is not repeated.
  1. Section 4.4.11 Added additional explanation of why 6 hour shelf life is recommended.
  1. Published