Preparing COVID-19 Vaccine Moderna syringes for administration at end user locations

Sue Dickinson, Director of Pharmacy, Regional Drug & Therapeutics Centre (Newcastle)Published Last updated See all updates

Standard Operating Procedures for preparing Moderna Spikevax® COVID-19 Vaccine syringes for administration at end user locations in primary care.

Information

The Conditions of Authorisation for Moderna Spikevax® COVID-19 vaccine have been amended to enable transportation at 2-8C of unopened vials in multiple journeys up to 12 hours in total.

Staff at all sites should discuss their plans with their clinical leads and responsible pharmacists as appropriate prior to transportation of any vaccine type.

Two different doses of the Moderna Spikevax® vaccine are used depending on whether administration is part of a primary immunisation course or being used as a booster.

Separate procedures and work instructions are now available for both the 0.5ml primary course and the 0.25ml booster dose.

Local systems must be in place to ensure that staff undertaking preparation have confirmed which dose is required and that only the correct dose specific supporting documents are in use during the preparation of the syringe for administration.

Standard operation procedures for each dose are attached to this page.

Within a SOP red text indicates where detail is to be added locally.  You should also familiarise yourself with our background guide before using these SOPs

These documents may be adapted by Superintendent Pharmacists for the use of the vaccine in community pharmacy settings.

Attachments

Other handling content for PCNs

Other COVID-19 vaccines resources

Change history

  1. Current content remains accurate
  1. Current content remains accurate
  1. MVH8.1a updated to remove reference to diluted vial
  1. MVH8 renamed as MVH 8a and updated to highlight this procedure is specific to the 0.5ml primary course dose. Added check that correct dose is being prepared and further advice to reduce risk of coring.
  2. MVH8.1 renamed MVH 8.1a and updated to highlight this instruction is specific to the 0.5ml primary course dose. Added check that correct dose is being prepared and further advice to reduce the risk of coring.
  3. MVH 8.3 updated to include both primary course and booster dose information
  4. MVH 8b and MVH 8.1b uploaded as new documents specific to the 0.25ml booster dose
  1. Data now available to support transportation of one or more thawed vials in liquid state for up to 12 hours at 2°C to 8°C (within the 30 days shelf life at 2°C to 8°C). SOP and supporting documents reinstated. Reference to use with vials received frozen removed
  2. MVH8 Section 5.3.17 Removal of outdated Foundry codes 6
  3. The name of the vaccine has changed to Spikevax®
  1. SOP suspended following confirmation that Moderna COVID-19 vaccine should not be used in mobile or roving settings if delivered in the thawed state
  1. Published