Preparing COVID-19 Vaccine Pfizer-BioNTech Syringes for Administration at end user locations

Amanda Cooper, Associate Director, Medicines Use and Safety TeamPublished Last updated See all updates

Standard Operating Procedure for preparing COVID-19 Vaccine Pfizer-BioNTech syringes for administration at end user locations in primary care.


A standard operating procedure is attached to this page.

These documents may be adapted by Superintendent Pharmacists for the use of the vaccine in Community Pharmacy settings.

You should also familiarise yourself with our background guide Facilitating Pharmaceutical support to PCN Designated Sites for COVID-19 vaccinations before using this SOP.



Other handling content for PCNs

Other COVID-19 vaccines resources

Other external resources

COVID-19 Vaccine Pfizer-BioNTech Handling and Preparation Video

A video produced by Pfizer showing the correct handling and preparation of the COVID-19 Vaccine Pfizer-BioNTech

What to do if you still have questions

If you still have questions you can get in touch with us. However, please first read our service remit; and if you still think we can help, use the email address below.

We're supporting healthcare professionals in England with pharmaceutical aspects of the COVID-19 vaccination programme; read our service remit to find out more.
If you're a healthcare professional in England, get in touch with us if you still have questions

Change history

  1. Addition of wording to webpage referring to use within Community Pharmacy settings.
  1. PVH8 - Clarification following update to national PGD, Clarification of disposal route for outer packaging
  1. Link to Pfizer video added
  1. PVH8 - Needle gauge options for morbidly obese amended, avoidance of pooling added and amended to six doses in line with updated regulation 174
  2. PVH8.1 - Amended in line with updated regulation 174
  3. PVH8.2 - Amended in line with updated regulation 174
  1. PVH8 - 5.4.1 - Additional consumables for sixth dose added
  2. PVH8 - 5.4.1 - Additional consumables for sixth dose added
  3. PVH8 - 5.3.1 - Clarification of swab type
  4. PVH8.2 - In line with PVH8 version 2.3 update. Minor clarifications and additon of consumables for sixth dose added into main text
  1. Published