Safety in Lactation: Anxiolytics.

Additional information relating to breastfeeding

To be used in conjunction with individual drug entries for specific information and guidance.

Use of anxiolytics in breastfeeding mothers should be approached with caution.

Many benzodiazepines have long half-lives and could potentially accumulate in the breastfed infant following prolonged administration, leading to possible sedation and increased risk of apnoea. The use of shorter acting agents, such as lorazepam and oxazepam, is preferred.

Where possible use short-term, intermittent dosing to reduce infant exposure.

Other drugs used for anxiety are not listed in this section, including duloxetine, oxprenolol, paroxetine,pregabalin, trazodone and venlafaxine.

AlprazolamBuspironeChlordiazepoxideDiazepamLorazepamMental health and illnessMeprobamateObstetrics and gynaecologyOxazepamPaediatric and neonatal medicineSafety in Lactation