Safety in Lactation: Non-steroidal anti-inflammatory drugs

There is very limited information on the use of NSAIDs during breastfeeding; ibuprofen and diclofenac are the preferred choices due to their extensive safe use during breastfeeding in clinical practice. If a cyclo-oxygenase-2 (COX-2) inhibitor is required, the preferred choice is celecoxib.
If a non-preferred NSAID is required, monitor the infant for gastro-intestinal side-effects, and avoid drugs with a long half-life, where possible, due to the potential risk of accumulation in the infant.