Safety in Lactation: Sympathomimetics for acute cardiac conditions

Sarah Fenner, Acting Co-Director, Midlands and East Medicines Advice Service (Midlands site) & UK Drugs in Lactation Advisory ServicePublished

Additional information relating to breastfeeding
To be used in conjunction with individual drug entries for specific information and guidance.

Dobutamine, dopamine and dopexamine are inotropes used in cardiac failure, shock and cardiac surgery. Ephedrine, metaraminol, noradrenaline and phenylephrine are used for acute hypotension. Adrenaline is used in cardiac arrest.

In all these acute clinical situations it is unlikely the mother will be breastfeeding, although the appropriate precautions will have to be followed if breastfeeding is resumed soon after drug administration.

Alternatives will  primarily depend on the acute clinical situation, rather than the risk in breastfeeding.