Shortage of Bile acid sequestrants: colestyramine powder for oral suspension 4g (Questran and Questran Light), colesevelam (Cholestagel) and colestipol (Colestid)

· London and South East Regional Medicines Information

Bristol-Myers Squibb divested the Questran range to Cheplapharm at the end of July 2019. This affected the availability of several bile acid sequestrants. The current stock situation is as follows:

  • Questran Light (Cheplapharm) – available in limited quantities
  • Questran (Cheplapharm) – out of stock; not expected before 2021
  • Colestyramine light 4g sachets (Mylan)– in stock
  • Cholestagel (colesevelam) 625mg tablets (Sanofi) – in stock
  • Colestid (colestipol) plain (Pfizer) – limited supplies currently available
  • Colestid (colestipol) Orange (Pfizer) – out of stock; until end of December 2020

This memo advises on management options until the shortage resolves.

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