Shortage of Miochol-E (acetylcholine) 20mg Powder and Solvent for Solution for Intraocular Irrigation

· London and South East Regional Medicines Information

Bausch and Lomb are experiencing long term supply issues, expected to last until mid September 2019. Miphtel® 20mg powder and solvent ampoules is an alternative product. When reconstituted, both these products provide a 20mg in 2ml (1%) acetylcholine solution. The indications, administration, pharmacokinetics and safety data is identical for both the products. The differences between the two acetylcholine products are highlighted in this memo.

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