Shortage of Ativan (lorazepam) Injection 4 mg in 1 ml

· London and South East Regional Medicines Information

Pfizer, the sole licensed UK supplier, is experiencing a supply issue. Pfizer is supplying an alternative presentation of lorazepam from the US during this time: Lorazepam 2mg/ml (Carpuject™) single dose cartridges (considered unlicensed in the UK), to support this out of stock period.  This memo advises on potential alternative agents that might be considered for use in the absence of a licensed version of lorazepam injection and if unlicensed lorazepam 2mg/ml single dose cartridges (Carpuject™) are not deemed appropriate.