This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care.   

The monitoring parameters cited are derived from a range of guideline sources, other reference sources and expert opinion and must therefore be considered suggestions only. Adherence to them will not ensure a successful outcome in every case. The ultimate judgement regarding a particular clinical result must be made by the doctor in light of the clinical data presented by the patient and the diagnostic and treatment options available.   For any enquiries contact David Erskine and Alison Alvey


New – SPS is changing the way we will present drug monitoring material in the future. We believe that there is a better way to display this high quality material to better meet users’ needs. We are creating an interactive on-line tool for therapeutic drug monitoring content which we are planning to release by April 2021. If you are involved with drug monitoring as part of your role and you would like to share your experience please get in touch (