Suggestions for Therapeutic Drug Monitoring in Adults in Primary Care

This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care.  Comments have been included as track changes to highlight areas where sources of national guidance differ or where no guidance on frequency is available and might be needed locally.  If you require a word version contact (

The monitoring parameters cited are derived from a range of guideline sources, other reference sources and expert opinion and must therefore be considered suggestions only. Adherence to them will not ensure a successful outcome in every case. The ultimate judgement regarding a particular clinical result must be made by the doctor in light of the clinical data presented by the patient and the diagnostic and treatment options available.