Refer to our full advice first
If you’ve not done so already, refer first to our full advice on morphine and opioid switching included in this series.
About the tool
Use our tool to calculate an estimated equivalent dose of oral morphine to other oral (non-morphine) opioids for pain management in adult cancer/palliative care patients.
Important note: the dose you calculate may not be the final dose recommended for your patient. You may need to apply a dose reduction – check whether this applies in our full advice on morphine and opioid switching.
The tool uses approximate potency equivalences obtained from a variety of information sources, including manufacturers’ data, specialist references, and published medical literature, to provide equivalence information for morphine and a selection of the more commonly prescribed oral opioids used in cancer and palliative care.
To convert from a non-morphine oral opioid to oral morphine, you will need to multiply the total daily dose of oral opioid by its potency equivalence, and to convert from oral morphine to a non-morphine oral opioid, you will need to divide the total daily dose of oral morphine by the potency equivalence for the oral opioid you are converting to.
The tool is not suitable for clinical settings other than palliative cancer care pain in adults, and is not suitable for routes of administration other than the oral route.
Use our example scenario to help you understand how to apply the tool in clinical practice.