UK Dental Medicines Advice Service (UKDMAS)

Christine Randall, Assistant Director, Lead pharmacist for Dental Medicines Information and Pharmacovigilance, North West Medicines Information CentrePublished

The UKDMAS service provides evidence based advice on the use of drugs in dentistry. The service is provided via the UK Medicines Information network by the North West Medicines Information Centre which is staffed by highly trained and experienced pharmacists.

Information Sources

The Service provides evidence based information on medicine related issues important to dental practice that have been identified during the course of delivering the UK dental enquiry answering service.

There are a number of evidence summaries (Q & As) available; the full list can be accessed here or via the links below.

What is the clinical significance of potential drug interactions with local anaesthetic preparations used in primary care dentistry?

Allergy to local anaesthetic agents used in dentistry – what are the signs, symptoms, alternative diagnoses and management options?

Using miconazole oral gel to treat oral thrush in adults taking a statin

Do patients with hydrocephalus shunts need antibiotic prophylaxis before undergoing dental procedures?

How should adults with cancer be managed by general dental practitioners if they need dental treatment?

Saliva substitutes: Choosing and prescribing the right product

What are the excipients in toothpastes?

Fluoride toothpaste – what are the dangers of chronic ingestion in adults?

When and how can dentists supply medicines?

How should dentists prescribe, store, order and dispose of controlled drugs?

What steroid supplementation is required for a patient with primary adrenal insufficiency undergoing a dental procedure?

SPS website

To find all documents related to dentistry from the home page type ‘dental’ into the search box.  This will bring up all pages where the word ‘dental’ appears in the title or subheading.  To further refine your search choose ‘oral and dental health’ from the suggested categories.  This will bring up all pages that have been keyworded with oral and dental health.


The service is provided to all health care professionals but is primarily used by dentists.

The types of enquiry answered include:

  • Appropriate use and choice of antibiotic for dental infections
  • use of prophylactic antibiotics for dental procedures
  • management of the dental patient on anticoagulants, antiplatelets or steroids
  • interactions and adverse effects associated with local anaesthetics
  • availability of pharmaceutical agents used in dentistry
  • medicines prescribing and legislation related NHS and private practice.

Contact the Service:

UKDMAS enquiry answering service is available from 08.30 – 17.00, Monday to Friday, excluding Bank Holidays

North West Medicines Information Centre

0151 794 8113

Information required when making an enquiry:

 For drug interaction enquiries:

  • is the enquiry prospective or retrospective
  • details of all medication the patient is taking
  • the underlying medical condition(s) the patient is being treated for
  • the dental indication for the potentially interacting drug


For antibiotic choice enquiries:

  • the dental condition for which the antibiotic is required
  • if the patient is allergic to a specific antibiotic, details of the previous allergic reaction
  • if the patient has received any antibiotics already for this condition
  • if any physical interventions have been attempted e.g. lancing an abscess
  • concomitant medicines


For antibiotic prophylaxis (endocarditis, joint replacement) enquiries:

  • the medical condition necessitating prophylaxis
  • the dental procedure necessitating prophylaxis
  • if the patient is allergic to any antibiotics
  • is this a one off or will the patient need to come back for several visits to complete the treatment


Dental prescribing enquiries:

  • is the patient an NHS or private patient?
  • the age of the patient
  • the indication for the prescription


Availability enquiries:

  • name of the product
  • dental use of the product
  • sources of information already used


Medicines information pharmacists should have looked in standard medicines information reference resources before calling the service; most interaction enquiries can be answered using texts such as the SPC, BNF and Stockley.

The centre has access to a wide range of standard medicines information textbooks, journals and databases plus specific dental resources. However, information from the published literature is not used in isolation and practical experience is available from dentists working in the Liverpool University Dental Hospital. We also maintain a large database of previous enquires.