Unpacking of frozen COVID-19 Vaccine Pfizer-BioNTech and transfer to fridges to thaw in Trusts without freezers

Ian Allen, Pharmacy Quality Assurance Regional Specialist (NW), North West Pharmaceutical Quality AssurancePublished Last updated See all updates

A standard operating procedure for unpacking frozen COVID-19 Vaccine Pfizer-BioNTech vaccines and transferring them to fridges to thaw is provided.


The attached standard operating procedure describes the process of unpacking frozen Pfizer-BioNTech COVID-19 vaccine and transfer to a fridge to thaw.


The attachment is presented in Word to enable adaptation locally, or as reference source to check that existing local procedures are robust and comprehensive.
Within the SOP:

  • GREEN TEXT indicates that detail is awaited, and will be added when available;
  • RED TEXT indicates where detail is to be added locally.


Other handling content for Trusts

Other COVID-19 vaccines resources

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Change history

  1. Updated to reflect availability of Comirnaty-branded products and associated changes
  1. New Pfizer thaw label image added
  1. Post thaw refrigerated expiry extended to 31 days
  1. Title slightly amended to "Unpacking of frozen Pfizer-BioNTech COVID-19 vaccine and transfer to fridges to thaw in Trusts without freezers"
  1. Published