Using COVID-19 Vaccine Moderna in Community Pharmacy

Amanda Cooper, Associate Director, Medicines Use and Safety TeamPublished Last updated See all updates

Requirements specific to the Moderna vaccine when used for the COVID-19 vaccination service within community pharmacy settings

Authorisation for use

The MHRA’s conditions of authorisation and the information for healthcare professionals and recipients outlines the framework through which the vaccine can be used.

Storing vaccine appropriately

The Moderna COVID-19 Vaccine delivered to Community Pharmacy does not require thawing and will already have been overlabelled with a thaw label and assigned a new expiry date.

Effective process control is essential to ensure that vaccines are stored correctly and new expiry dates/times are allocated.

Initial storage

Moderna COVID-19 mRNA Vaccine (nucleoside modified) may be stored for up to 30 days between 2°C and 8°C, followed by an additional 12 hours at room temperature.

Storage following first puncture

After the vial is first punctured it should be used as soon as practically possible and within 6 hours.

Storage and transit

Transit of the product between 2°C and 8°C should be minimised but may occur for a maximum of 12 hours.

Handling and preparing vaccine

Extracting additional doses

The vials are multi dose containers and contain 11 doses in each vial.

In order to extract 11 doses from a single vial, low dead-volume syringes and or needles should be used. If standard syringes and needles are used, there may not be sufficient volume to extract an 11th dose from a single vial.

When extracting additional doses, also remember (irrespective of the syringe and needle used) that:

  • Each dose must contain 0.5 mL of vaccine
  • If the amount of vaccine remaining in the vial cannot provide a full dose of 0.5 mL, discard the vial and any excess volume
  • Do not pool excess vaccine from multiple vials

If it is not possible to withdraw an 11th dose, the waste category “no 11th dose available” should be recorded as a free text comment on the Foundry stock control system.

Administration

Administration requires diligent process control to ensure the vaccine is safe and effective at the point of use.

Use in relation to prior allergy

Prior to administration, prior allergy status should be checked.

Advising individuals with allergies on their suitability for COVID-19 Vaccine AstraZeneca

Advice on whether people with a previous allergic reaction can have the COVID-19 Vaccine AstraZeneca.

Process flow for vaccination session

A diagram giving an overview of the process during a vaccination session is attached below.

SOPs, work instructions and checklists to adapt

Relevant Standard Operating Procedures, work instructions and checklists are available below. These may be adapted by Superintendent Pharmacists for use in Community Pharmacy settings.

Receiving and storing COVID-19 Vaccine Moderna at PCN designated Sites

30 April 2021Standard Operating Procedure for PCN designated sites receiving and storing the COVID-19 Vaccine Moderna

Preparing COVID-19 Vaccine Moderna at PCN Designated Sites

30 April 2021Standard Operating Procedure for preparation of the Moderna COVID-19 Vaccine in PCN designated sites prior to immediate administration.

Stocktaking and reconciliation of COVID-19 Vaccine Moderna at PCN designated sites

30 April 2021Standard Operating Procedure for stocktaking and reconciliation of COVID-19 Vaccine Moderna from PCN designated sites to end user locations.

Disposing of damaged, unused or expired COVID-19 Vaccine Moderna at PCN designated sites

30 April 2021Standard Operating Procedure for safe disposal of damaged, unused, or expired COVID-19 Vaccine Moderna consigned for destruction at PCN Designated Sites

Dealing with spillages and breakages of COVID-19 vaccine Moderna at PCN designated sites

30 April 2021Standard Operating Procedure for PCN designated sites for dealing with spillages or breakages of the COVID-19 vaccine Moderna

Transporting COVID-19 Vaccine Moderna from PCN designated sites to end user locations

30 April 2021Standard Operating Procedure for transporting COVID-19 Vaccine Moderna from PCN designated sites to end user locations.

Preparing COVID-19 Vaccine Moderna at PCN Designated Sites

30 April 2021Standard Operating Procedure for preparation of the Moderna COVID-19 Vaccine in PCN designated sites prior to immediate administration.

Change history

  1. Amendment to wording on webpage re multidose vial
  1. Published