Authorisation for use
The MHRA’s conditions of authorisation and the information for healthcare professionals and recipients outlines the framework through which the vaccine can be used.
Storing vaccine appropriately
The Moderna COVID-19 Vaccine delivered to Community Pharmacy does not require thawing and will already have been overlabelled with a thaw label and assigned a new expiry date.
Effective process control is essential to ensure that vaccines are stored correctly and new expiry dates/times are allocated.
Moderna COVID-19 mRNA Vaccine (nucleoside modified) may be stored for up to 30 days between 2°C and 8°C, followed by an additional 12 hours at room temperature.
Storage following first puncture
After the vial is first punctured it should be used as soon as practically possible and within 6 hours.
Storage and transit
Transit of the product between 2°C and 8°C should be minimised but may occur for a maximum of 12 hours.
Handling and preparing vaccine
Extracting additional doses
The vials are multi dose containers and contain 11 doses in each vial.
In order to extract 11 doses from a single vial, low dead-volume syringes and or needles should be used. If standard syringes and needles are used, there may not be sufficient volume to extract an 11th dose from a single vial.
When extracting additional doses, also remember (irrespective of the syringe and needle used) that:
- Each dose must contain 0.5 mL of vaccine
- If the amount of vaccine remaining in the vial cannot provide a full dose of 0.5 mL, discard the vial and any excess volume
- Do not pool excess vaccine from multiple vials
If it is not possible to withdraw an 11th dose, the waste category “no 11th dose available” should be recorded as a free text comment on the Foundry stock control system.
Administration requires diligent process control to ensure the vaccine is safe and effective at the point of use.
Use in relation to prior allergy
Prior to administration, prior allergy status should be checked.
Process flow for vaccination session
A diagram giving an overview of the process during a vaccination session is attached below.
SOPs, work instructions and checklists to adapt
Relevant Standard Operating Procedures, work instructions and checklists are available below. These may be adapted by Superintendent Pharmacists for use in Community Pharmacy settings.
- Amendment to wording on webpage re multidose vial