What is the equivalent dose of oral prednisolone to intravenous (IV) hydrocortisone?

· UKMi

  • Prednisolone 5mg orally is equivalent to hydrocortisone 20mg intravenously (equivalent anti-inflammatory dose).
  • The peri-operative dose of hydrocortisone required may be higher than the equivalent prednisolone dose usually taken by the patient.
  • The equivalent doses given in this Q&A are approximations and may not apply to all disease states and to all patients.
  • This information should not be used in emergency situations such as in the management of acute severe asthma.
HydrocortisonePrednisoloneQ&A

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