What is the most suitable treatment for acne in a patient with acute porphyria?

· UKMi

  • Topical treatments for acne are considered to be safer than oral treatments in patients with an acute form of porphyria, provided they are applied to intact skin.
  • Topical benzoyl peroxide is known to be safe in acute porphyria and should be used first-line, if appropriate.
  • Oral erythromycin and oral contraceptives (oestrogens and progestogens) are known to be porphyrinogenic and should be avoided in patients with an acute form of porphyria requiring treatment for acne.
AdapaleneBenzoyl peroxideClindamycinDoxycyclineErythromycinIsotretinoinLymecyclineNutritional and metabolic disordersQ&ASkin disordersTretinoin