Which medicines require extra care when switching between liquid and tablet/capsule formulations?

For a small number of medicines, there are differences in equivalent doses of oral formulations of the same medicine. This Q&A considers which medicines may require dose adjustment when switching between oral formulations and presents information on dose adjustment in a summary table.  In instances where it may not be possible to achieve a dose that is exactly the same, practical advice such as additional patient monitoring is suggested. Other concerns relating to the suitability of the formulation for the patient are discussed.


AlfacalcidolCarbamazepineChloral hydrateCitalopramClomethiazoleClozapineCo-amoxiclavDigoxinEmtricitabineFusidic acidItraconazoleLithiumMebeverineMedicineMedicines SafetyMercaptopurineMetronidazoleMycophenolate mofetilMycophenolic acidPhenytoinPhenytoin sodiumPosaconazoleQ&ARaltegravirSelegilineSirolimusTenofovirTipranavirValproic acidVardenafil