Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…
This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care. Comments have been included as…
A UKMi Product Safety assessment for Prednisolone Dompe 1mg/mL Oral Solution describes the in-use medication safety considerations resultant from the product’s presentation or other pre-defined…
Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Aminosalicylates for chronic bowel disorders Mesalazine…
A UKMi Product Safety assessment for the Pevanti® (prednisolone tablet) range which describes the in-use medication safety considerations resultant from the product’s presentation or other…
Prednisolone 5mg orally is equivalent to hydrocortisone 20mg intravenously (equivalent anti-inflammatory dose). The peri-operative dose of hydrocortisone required may be higher than the equivalent prednisolone…
When this topic was reviewed in the two Drug and Therapeutics Bulletins (DTBs) several decades ago, no convincing evidence was found to support the claim…
Fludrocortisone is used mainly for mineralocorticoid replacement in adrenocortical insufficiency. The other drugs in this group are used mainly for their anti-inflammatory, glucocorticoid activity, although…
Preparations for treating otitis externa have limited systemic absorption in the mother, and pose negligible risk to a breastfed infant. There is no published evidence…