What is the most appropriate antidepressant to use in people with epilepsy?

NICE recommend that non-pharmacological interventions such as CBT should be considered in people presenting with depression, in addition to the use of antidepressants. With respect…

Which oral vitamin D dosing regimens correct deficiency in pregnancy?

This UKMi Q&A evaluates the available evidence at the time of publication to address issues associated with vitamin D dosing in pregnancy

What information is available on drugs in diving?

There are several sources of information on drugs and medical conditions that may affect a person’s ability to dive. Professional divers are required by law…

Which opioids can be used in renal impairment?

Opioids are used in a wide variety of clinical settings and are well established for the treatment of both acute and chronic pain. Renal impairment…

What is the risk of interaction between opioids and monoamine oxidase inhibitors (MAOIs)?

This article considers the risks of interaction between opioids and monoamine oxidase inhibitors. The use of MAOIs with opioids is contraindicated or cautioned by manufacturers.…

What is the first choice antidepressant for patients with renal impairment?

This updated Medicines Q&A evaluates the limited published evidence available on the use of antidepressants in patients with renal impairment. The use of antidepressants in…

Which medicines require extra care when switching between liquid and tablet/capsule formulations?

For a small number of medicines, there are differences in equivalent doses of oral formulations of the same medicine. This Q&A considers which medicines may…

NOACs and Antidepressants – What are the risks of using these together and how should these risks be managed?

This article considers the risk of interactions between NOACs and antidepressants. ·        Non-vitamin K antagonist oral anticoagulants (NOACs) appear to have fewer clinically significant drug…

Statins - What is the evidence for their use in patients with renal impairment?

This Q&A evaluates the evidence for the use of statins in renal impairment and discusses current guidance for using statins in this population.

Turmeric: potential adverse effects and interactions

Turmeric has been widely used in traditional medicine and as a spice in foods Curcumin is the main active ingredient in turmeric. Turmeric and curcumin…