Mental health and illness

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MAOI to other antidepressants: switching in adults

17 February 2023Switching between or from a monoamine oxidase inhibitor (MAOI) is always a complex switch and you should follow specialist advice.

Moclobemide to other antidepressants: switching in adults

17 February 2023How to switch safely from moclobemide to other antidepressants. Seek specialist advice for complex switches.

Trazodone to other antidepressants: switching in adults

17 February 2023How to switch safely from trazodone to other antidepressants. Seek specialist advice for complex switches.

Vortioxetine to other antidepressants: switching in adults

17 February 2023How to switch safely from vortioxetine to other antidepressants. Seek specialist advice for complex switches.

SNRIs to other antidepressants: switching in adults

17 February 2023How to switch safely between serotonin and noradrenaline reuptake inhibitors (SNRIs) or to other antidepressants. Seek specialist advice for complex switches.

Agomelatine to other antidepressants: switching in adults

17 February 2023How to switch safely from agomelatine to other antidepressants. Seek specialist advice for complex switches.

Mirtazapine to other antidepressants: switching in adults

17 February 2023How to switch safely from mirtazapine to other antidepressants. Seek specialist advice for complex switches.

Choosing an antidepressant to switch a person to

17 February 2023Where a need to switch antidepressant is established, appraise the options to identify what's suitable for the person. For complex switches: consult an expert.

Establishing whether a person needs to switch their antidepressant

17 February 2023Prior response, side-effects, new contraindications, and current symptoms may make an antidepressant switch necessary. When it is, establish shared goals.

Monitoring a person during and after antidepressant switching

17 February 2023Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of discontinuation and serotonin syndromes.

SPS - Specialist Pharmacy Service

NHS