Maintaining the cold chain is vital to ensure vaccine efficacy. Excursions should be investigated appropriately, causes identified, and corrective action taken.

Maintaining the vaccine cold chain: read first

Correct storage of the vaccine ensures its efficacy and the cold chain must be maintained during storage and transportation
Higher temperatures increase risks to safe vaccine use and storage. To minimise effects: control ambient temperature, assess risks, and mitigate against them.

Additional material

Receiving of thawed Moderna vaccine in Trusts

Instructions for receiving thawed Moderna vaccines are provided.

Extending the post thaw expiry of Moderna (Spikevax) COVID-19 vaccine in PCN designated sites

Extension of the post thaw expiry of Moderna (Spikevax) COVID-19 vaccine is no longer supported by Moderna.

Extending the post thaw expiry of Moderna (Spikevax) COVID-19 vaccine in Trusts and Vaccination Centres

Extension of the post thaw expiry of Spikevax® COVID-19 vaccine is no longer supported by Moderna.

Extending the post thaw expiry of Comirnaty (30 microgram/dose) concentrate for Adults and Adolescents at PCN designated sites

Extension of the post thaw expiry of Comirnaty (30 microgram/dose) concentrate for Adults and Adolescents is no longer supported by Pfizer

Extending the post thaw expiry of Comirnaty (30 microgram/dose) concentrate for Adults and Adolescents in Trusts

Extension of the post thaw expiry of Comirnaty (30 microgram/dose) concentrate for Adults and Adolescents is no longer supported by Pfizer

Defrosting Comirnaty concentrate vaccine for adults and adolescentsCOVID-19 Vaccine Pfizer-BioNTech

The Comirnaty concentrate for adults and adolescents must be defrosted before use. This page gives guidance on considerations whilst thawing the vaccine.

Using COVID-19 vaccines during hot weather

Higher temperatures increase risks to safe vaccine use and storage. To minimise effects: control ambient temperature, assess risks, and mitigate against them.

Quality Improvement Alert - Cold Chain Management of COVID-19 Vaccines

An SPS quality improvement alert to highlight the requirements for safe and effective cold storage of COVID-19 vaccines

Using CorrMed Cool Bags for Vaccine Storage

Information and guidance on the use of CorrMedCoolboxes. Refers to storage for all vaccines across all care settings.