Resources covering AstraZeneca pharmaceutical processes in Trusts, from initial ordering through to administration

Resources covering AstraZeneca pharmaceutical processes in Trusts, from initial ordering through to administration

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Resources underpinning pharmaceutical processes in Trusts and Vaccination Centres for all vaccines
Must read guidance for Chief Pharmacists and others in Trusts on the Vaxzevria Vaccine.
COVID-19 vaccines have different handling and dosing requirements. Sites need to plan to reduce the risk of errors where multiple vaccines are available.

Standard Operating Procedures

Each SOP and a summary of all major changes is provided.

Ordering Vaxzevria Vaccine for Trusts

Change history
  1. · Removal of reference to Regulation 174 product. Vaxzevria vaccine now ordered using foundry system.
  2. · Reference to Public Health England or PHE in the title removed.
  3. · Reference to Public Health England or PHE amended to UK Health Security Agency or UKHSA, SOP title updated accordingly, removed reference to patient factsheets initially only being available electronically, and references updated.
  4. · Page title changed from Ordering COVID-19 Vaccine AstraZeneca from Public Health England (PHE) for Trusts to Ordering COVID-19 Vaccine AstraZeneca from UK Health Security Agency (UKHSA - formerly known as PHE) for Trusts
  5. · Resources checked and information remains correct.
    1. · Detail on local ordering system removed and ordering via Immform updated.
    2. · Page updated with link to page on dealing with delivery issues.
    3. · Published

Receipt of refrigerated Vaxzevria Vaccine by Trusts

Change history
  1. · Removal of reference to Regulation 174 product and updated throughout to reflect change in name for the licensed product (Vaxzevria).
  2. · Resources checked and information remains correct.
  3. · Reference to Public Health England or PHE amended to UK Health Security Agency or UKHSA, and references updated.
  4. · Resources checked and information remains correct.
  5. · Removed ‘agent to be confirmed’ in relation to antiviral disinfectant
    1. · Published

Preparing Vaxzevria Vaccine in Trusts

Change history
  1. · Removal of reference to Regulation 174 product and updated throughout to reflect change in name for the licensed product (Vaxzevria).
  2. · Resources checked and information remains correct.
  3. · AZH3 Reference to Public Health England or PHE amended to UK Health Security Agency or UKHSA, added sentence to check the vial is within the manufacturers expiry printed on the vial, and references updated. AZH3.1 Added sentence to check the vial is within the manufacturers expiry printed on the vial.
  4. · Resources checked and information remains correct.
  5. · Resources checked and information remains correct.
    1. · AZH3 Amended to state that outer packaging must be disposed of as confidential waste.
    2. · AZH3 4.3.13 Change of zero character with Celsius character.
    3. · AZH3 Wording amended in section 4.3.12 to 4.3.14 for clarity on actions required.
    4. · AZH3 Wording amended on section 4.3.14 to 4.3.15 providing further clarity on actions required.
    5. · AZH3.1 Picture of syringe updated
    6. · Clarification of wording about removing of vaccine vials from refrigerator.
    7. · Avoidance of pooling added.
    8. · Amended needle gauge options for morbidly obese patients in accordance with PHE guidance.
    9. · Clarification on working under the national PGD and inclusion of extra consumables for additional doses incorporated into main text.
    10. · Withdrawing additional doses information added.
    11. · Published

Institutional Readiness for management of Vaxzevria Vaccine in Trusts

Change history
  1. · Removal of reference to Regulation 174 product and updated throughout to reflect change in name for the licensed product (Vaxzevria).
  2. · Reference to Public Health England or PHE in the purpose section on the page removed.
  3. · Reference to Public Health England or PHE amended to UK Health Security Agency or UKHSA, and removed reference to patient factsheets initially only being available electronically.
  4. · Section on mutual aid and transfer of COVID-19 vaccine between hospital hubs, vaccination centres and local vaccination services added.
  5. · Link to NHSE position statement about microbial risk associated with movement of punctured vials added.
    1. · Broken hyperlinks updated.
    2. · Addition of new link to IT Policy document on SPS website.
    3. · Wording amended to clarify that outer packaging must be disposed of as confidential waste.
    4. · Amended link for to best practice for storing COVID-19 vaccines in the refrigerator
    5. · Minor amendment to wording linking to V1 IT Policy and removal of 'agent to be confirmed' for antiviral disinfectant.
    6. · Quantity of vials in each carton corrected. Page numbers amended.
    7. · Included hyperlink to ‘Deployment of COVID-19 Vaccine Oxford/AstraZeneca: implications for governance, handling and preparation of vaccines’ letter
    8. · Published

Training resources

AstraZeneca Vaccine: Handling in Trusts and Vaccination Centres

Resources covering AstraZeneca pharmaceutical processes in Trusts, from initial ordering through to administration

Other COVID-19 vaccines resources