Resources covering Pfizer-BioNTech pharmaceutical processes in Trusts, from initial ordering through to administration

Read first

Resources underpinning pharmaceutical processes in Trusts and Vaccination Centres for all vaccines
Must read guidance for Chief Pharmacists and others in Trusts on the COVID-19 Vaccine Pfizer-BioNTech.
COVID-19 vaccines have different handling and dosing requirements. Sites need to plan to reduce the risk of errors where multiple vaccines are available.

Standard Operating Procedures

Each SOP and a summary of all major changes is provided.

Ordering COVID-19 Vaccine Pfizer-BioNTech from Public Health England (PHE) for Trusts

Change history
  1. · Detail on local ordering system removed and link to NHS England SOP on ordering added.
  2. · Published

Receiving of frozen COVID-19 Vaccine Pfizer-BioNTech in ultra-low temperature freezers in Trusts

  1. · Published · This article has not changed since

Unpacking and storing frozen COVID-19 Vaccine Pfizer-BioNTech in ultra-low temperature freezers in Trusts

  1. · Published · This article has not changed since

Unpacking of frozen COVID-19 Vaccine Pfizer-BioNTech and transfer to fridges to thaw in Trusts without freezers

Change history
  1. · New Pfizer thaw label image added
  2. · Post thaw refrigerated expiry extended to 31 days
  3. · Title slightly amended to "Unpacking of frozen Pfizer-BioNTech COVID-19 vaccine and transfer to fridges to thaw in Trusts without freezers"
  4. · Published

Moving COVID-19 Vaccine Pfizer-BioNTech Vaccines from an ULT freezer into a fridge to thaw in Trusts

Change history
  1. · New Pfizer thaw label image added
  2. · Post thaw refrigerated expiry extended to 31 days
  3. · Published

Thawing small numbers of COVID-19 Vaccine Pfizer-BioNTech vials

Change history
  1. · New Pfizer thaw label image added with extended 31 day expiry
  2. · Published

Cryocube F101-h Freezer Temperature Monitoring and Recording in Trusts

  1. · Published · This article has not changed since

Preparing COVID-19 Vaccine Pfizer-BioNTech in Trusts

Change history
  1. · VH8 Amended instructions for disposal of cartons to include placing in confidential waste
  2. · VH8, VH8.1 and VH8.2 updated to describe withdrawal of 6 doses as standard practice
  3. · VH8 4.4.1, VH8.1 and VH8.2 updated to include additional references to 6th dose
  4. · VH8 4.1.7 addition of 2nd check to include correct vaccine vial selected
  5. · VH8 4.4.4 Now states “new” syringe / needle must be used
    1. · VH8 Section 2 updated to include model of one person diluting and drawing up
    2. · VH8.1 updated to reflect the change
    3. · Change to SOP VH8 Section 4.3.4, regarding presence of opaque particles prior to dilution
    4. · Published

Institutional Readiness for Managing COVID-19 Vaccine Pfizer-BioNTech in Trusts

Change history
  1. · Post thaw refrigerated expiry extended to 31 days
  2. · Added SOP for thawing small numbers of vaccine vials
  3. · Amendment of instructions for disposal of cartons to use of confidential waste stream, plus various minor updates - see change log in document
  4. · Published

Training Resources

COVID-19 Vaccine Pfizer-BioNTech pathway critical control points presentation for Trusts

A guidance presentation for process supervisors on COVID-19 Vaccine Pfizer-BioNTech pathway critical control points

COVID-19 Vaccine Pfizer-BioNTech Handling and Preparation Video

A video produced by Pfizer showing the correct handling and preparation of the COVID-19 Vaccine Pfizer-BioNTech

Pfizer-BioNTech: Handling in Trusts and Vaccination Centres

Resources covering Pfizer-BioNTech pharmaceutical processes in Trusts, from initial ordering through to administration

Other COVID-19 vaccines resources