Resources covering Pfizer-BioNTech pharmaceutical processes in Trusts, from initial ordering through to administration

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Resources underpinning pharmaceutical processes in Trusts and Vaccination Centres for all vaccines
Must read guidance for Chief Pharmacists and others in Trusts on the Pfizer-BioNTech COVID-19 vaccine.
COVID-19 vaccines have different handling and dosing requirements. Sites need to plan to reduce the risk of errors where multiple vaccines are available.

Standard Operating Procedures

Each SOP and a summary of all major changes is provided.

Ordering Pfizer-BioNTech COVID-19 Vaccine from Public Health England (PHE) for Trusts

Change history
  1. · Detail on local ordering system removed and link to NHS England SOP on ordering added.
  2. · Published

Receipt of frozen vaccine in ultra-low temperature freezers in Trusts

  1. · Published · This article has not changed since

Unpacking of frozen Pfizer-BioNTech COVID-19 vaccine and transfer to fridges to thaw in Trusts without freezers

Change history
  1. · Title slightly amended to "Unpacking of frozen Pfizer-BioNTech COVID-19 vaccine and transfer to fridges to thaw in Trusts without freezers"
  2. · Published

Moving Pfizer-BioNTech COVID-19 Vaccines from an ULT freezer into a fridge to thaw in Trusts

  1. · Published · This article has not changed since

Cryocube F101-h Freezer Temperature Monitoring and Recording in Trusts

  1. · Published · This article has not changed since

Preparing Pfizer-BioNTech Vaccine in Trusts

Change history
  1. · VH8 Amended instructions for disposal of cartons to include placing in confidential waste
  2. · VH8, VH8.1 and VH8.2 updated to describe withdrawal of 6 doses as standard practice
  3. · VH8 Section 2 updated to include model of one person diluting and drawing up
  4. · VH8 4.4.4 Now states “new” syringe / needle must be used
  5. · VH8 4.1.7 addition of 2nd check to include correct vaccine vial selected
    1. · VH8 4.4.1, VH8.1 and VH8.2 updated to include additional references to 6th dose
    2. · Change to SOP VH8 Section 4.3.4, regarding presence of opaque particles prior to dilution
    3. · VH8.1 updated to reflect the change
    4. · Published

Institutional Readiness for Management of Pfizer-BioNTech COVID-19 vaccine in Trusts

Change history
  1. · Amendment of instructions for disposal of cartons to use of confidential waste stream, plus various minor updates - see change log in document
  2. ·
  3. · Published

Training Resources

Pfizer-BioNTech Vaccine pathway critical control points presentation for Trusts

A guidance presentation for process supervisors on Pfizer-BioNTech Vaccine pathway critical control points

Pfizer-BioNTech Vaccine Handling and Preparation Video

A video produced by Pfizer showing the correct handling and preparation of the Pfizer-BioNTech COVID-19 vaccine

Poster to support staff when handling Pfizer-BioNTech COVID-19 vaccine for Trusts and PCN sites

The poster can be downloaded, printed, and displayed in clinical areas to support implementation of Pfizer-BioNTech vaccination Standard Operating Procedures.

Other COVID-19 vaccines resources