Alverine + simeticone

34277711000001106

New Medicines

SimAlvia · Relief of abdominal pain in adults with irritable bowel syndrome

Information

SimAlvia
New formulation
HFA Healthcare
Not Known

Development and Regulatory status

Launched
Launched
None
September 2020
Sep 20 · Available in the UK. SimAlvia 60 mg/300 mg, soft capsules are licensed for relief of abdominal pain in irritable bowel syndrome in adults. Price, 90=£11.00 [3].
Dec 14 · After a subsequent national phase, the UK granted a MAA [2].
Nov 14 · Following a review using the decentralised procedure in which Laboratoires GALENIQUES VERNIN had applied for a licence in Belgium and the Republic of Ireland (concerned Member States), and the UK acting as Reference Member State (RMS), all agreed that marketing authorisation should be granted [2].

Category

Alverine citrate is a non-atropinic, papaverine-like musculotropic antispasmodic. Simeticone is an inert substance which has a physical action by altering the surface tension of gas bubbles, leading to their coalescence.
IBS occurs in 10-20% of the population in the UK, but prevalence is thought to be higher than this as many people with the disorder do not seek medical advice [1].
Relief of abdominal pain in adults with irritable bowel syndrome
Oral

Evidence based evaluations