2 July 2021Prescribers may need to choose a safe antidepressant in people with CHD. We guide on available options. We do not cover management of complex depression.
21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…
22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.
21 October 2019This updated Medicines Q&A provides advice on the risks and suggested strategies for switching between tricyclic (TCA), selective serotonin reuptake inhibitors (SSRI) and related antidepressants.…
10 June 2019This Medicines Q&A evaluates the evidence available on the management of depression in patients with antidepressant-induced hyponatraemia. Summary Most antidepressants are associated with hyponatraemia, with…
Medicine Compliance Aid Stability
genericAccord Healthcare Ltd
Accord Healthcare Ltd
Tablets f/c 10mg, 25mg, 50mg
A3 · Amber 3 No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from light and store in an airtight container.
7 January 2022
Lactation Safety Information
Limited published evidence of safety indicates small amounts in breast milk
Long half-life increases risk of accumulation in breastfed infants
Case report of an infant with poor feeding and sedation possibly due to maternal amitriptyline
Monitor infants for drowsiness, poor feeding and irritability/behavioural effects
29 July 2020