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How do amlodipine and felodipine compare for the treatment of hypertension or prophylaxis of stable angina?

25 September 2020This updated Medicines Q&A reviews the data available to assist decision-making when choosing and switching between amlodipine and felodipine for the treatment of hypertension or…

Safety in Lactation: Drugs for hypertension

23 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Many of the drugs covered by…

How should ankle oedema caused by calcium channel blockers be treated?

1 June 2020Ankle oedema is a common, often troublesome adverse effect for patients who are receiving calcium channel blocker (CCB) therapy, and may affect compliance. It is…

What are the reported incidences of ankle oedema with different calcium channel blockers?

1 June 2020The potential to cause ankle oedema appears to exist for all calcium channel blocking agents, and is caused by increasing capillary pressure leading to leakage…
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Refrigerated Storage

AmlodipineRosemont Pharmaceuticals Ltd

Rosemont Pharmaceuticals Ltd
Amlodipine
Oral solution (1mg/ml and 2mg/ml)

Contact Rosemont Pharmaceuticals Ltd in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

7 October 2021

Amlodipine ThameThame Laboratories

Thame Laboratories
Amlodipine Thame
Oral solution (5mg/5ml and 10mg/5ml)

Contact Thame Laboratories in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

7 October 2021

Medicine Compliance Aid Stability

IstinPfizer Ltd

Pfizer Ltd
Istin
Tablets 5mg, 10mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Disintegrates in presence of small amount of water.
9 November 2015

Lactation Safety Information

Nifedipine, Verapamil
Moderate level of published evidence of use in breastfeeding
Long half-life increases risk of accumulation in breastfed infants
Variable amounts in breast milk
Monitor infant for adverse effects
Used in infants >1 month
16 September 2019