Medicines that are considered safe for use in the acute porphyrias

29 May 2020The UK Porphyria Medicines Information Service (UKPMIS) and Cardiff Porphyria Service produce a list of medicines that are considered to be safe for use in…
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Refrigerated Storage


Powder for concentrate for solution for infusion

In the event of an inadvertent temperature excursion the following data may be used:
Excursions up to a cumulative time of 96 hours at temperatures up to 25°C are permitted, and the powder can be returned to refrigerated storage.
Contact Pfizer in cases where additional stability data is required. Refer to the electronic medicines compendium (eMC) at for company contact details.

2 March 2022
London MI Service

Lactation Safety Information

Fluconazole, if clinically appropriate
Low levels anticipated in milk due to the drug's properties
No published evidence of safety
Not absorbed from the infant's GI tract
Monitor infant for gastro-intestinal disturbances, especially if used for prolonged periods or in high doses, although unlikely to occur.
3 November 2020