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Safety in Lactation: Antipsychotics

22 September 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral and non-depot antipsychotics with less…

Medicines that are considered safe for use in the acute porphyrias

29 May 2020The UK Porphyria Medicines Information Service (UKPMIS) and Cardiff Porphyria Service produce a list of medicines that are considered to be safe for use in…
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Medicine Compliance Aid Stability

AbilifyOtsuka Pharmaceuticals UK Ltd

Otsuka Pharmaceuticals UK Ltd
Abilify
Tablets 5mg, 10mg, 15mg, 30mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Hygroscopic protect from moisture. Maximum of 7 days in MCA.
1 October 2015

Abilify OrodispersibleOtsuka Pharmaceuticals UK Ltd

Otsuka Pharmaceuticals UK Ltd
Abilify Orodispersible
Tablets orodispersible 10mg, 15mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Protect from moisture. Orodispersible in nature therefore likely to be hygroscopic.
1 October 2015

generic (Caduceus)Actavis UK Ltd

Actavis UK Ltd
generic (Caduceus)
Tablets orodispersible 10mg, 15mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Protect from moisture. Orodispersible in nature therefore likely to be hygroscopic.
1 October 2015

genericConsilient Health Ltd

Consilient Health Ltd
generic
Tablets 5mg, 10mg, 15mg, 30mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Hygroscopic protect from moisture. Maximum of 7 days in MCA.
1 October 2015

Lactation Safety Information

Oral / depot injection

Oral / depot injection
Caution
Quetiapine, Haloperidol
Very limited published evidence shows that maternal doses up to 15mg daily produce low levels in breast milk
Long half-life increases risk of accumulation in breastfed infants
Anecdotal unpublished reports of somnolence in breastfed infants
Monitor infant for sedation, poor feeding, behavioural effects, extrapyramidal symptoms, and developmental milestones
Possible effect on prolactin may decrease milk supply
22 January 2020