dm+d

Unassigned

New Medicines

BegedinaAcute steroid-resistant graft versus host disease (GvHD)

Information

Begedina
New molecular entity
Adienne
Not Known

Development and Regulatory status

Phase III Clinical Trials
Phase III Clinical Trials
Phase III Clinical Trials
Yes
Yes

Category

A murine antibody that is directed against CD26 antigen expressed on haematopoietic progenitor cells (CD4 T lymphocytes).
Immunosuppressed patients who receive white blood cells from another person are at risk of GVHD. The incidence of acute GVHD varies widely ranging from 10-80%, depending on risk factors [2].
Acute steroid-resistant graft versus host disease (GvHD)
Intravenous

Evidence based evaluations