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Articles

Safety in Lactation: Topical preparations for eczema and psoriasis

23 September 2020Topical preparations for eczema and psoriasis are considered to pose a negligible risk to a breastfeeding infant as long as precautions are taken to avoid…
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Lactation Safety Information

Topical

Topical
Yes
No published evidence relating to use in breastfeeding
Considered to be negligible risk provided precautions taken to avoid direct contact of the breastfeeding infant with treated areas. If applied to breast area, ensure removal from breast and nipple before feeding.
When using topical preparations on the breast creams are preferred (if available) to ointments due to ease of removal before breastfeeding
25 May 2022

New Medicines

Psoriasis of the nails - nail laquer formulation

Information

New formulation
Polichem
Polichem

Development and Regulatory status

Discontinued
Discontinued
Discontinued
Dec 20Development discontinued [5].

Category

An anhydrous calcipotriol (a synthetic derivative of calcitriol, a form of vitamin D) for administration as medicated nail lacquer,
The prevalence of psoriasis is estimated to be about 1.3-2.2% in the UK [1]. Nail changes occur in about half of all people with psoriasis and in about 4 in every 5 people with psoriatic arthritis [2].
Psoriasis of the nails - nail laquer formulation
Topical

Trial or other data

Jan 18PIII trial (NCT03079973) has been withdrawn due to a change in project development priorities [4].